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[肺动脉分支实验性栓塞时心肌的微循环床]

[The microcirculatory bed of the myocardium in experimental embolism of the branches of the pulmonary artery].

作者信息

Frolov V A, Tokmachev Iu K, Zhukov G V, Lazebnik L B

出版信息

Patol Fiziol Eksp Ter. 1990 Jan-Feb(1):25-7.

PMID:2352775
Abstract

Experiments were conducted on rabbits to appraise the condition of the myocardial microcirculatory channel (MCC) in embolism of branches of the pulmonary artery and to determine the dynamics of changes in the MCC with explanation of the mechanisms of their compensation. Mobilization of nonfunctioning capillaries in the healthy myocardium was revealed in the early postembolism period. Compensatory reaction of the thebesian drainage from the 1st to 7th day after the embolism was demonstrated. Ultrastructural changes of the myocardial MCC were found in embolism of the branches of the pulmonary artery. Vulnerability of the posterior parts of the left-ventricular myocardium and the anterior wall of the right ventricle in relation to insufficiency of coronary blood supply in embolism of the branches of the pulmonary artery was noted.

摘要

在兔子身上进行了实验,以评估肺动脉分支栓塞时心肌微循环通道(MCC)的状况,并确定MCC的变化动态及其代偿机制。在栓塞后的早期发现了健康心肌中未发挥功能的毛细血管的动员。证实了栓塞后第1天至第7天Thebesian引流的代偿反应。在肺动脉分支栓塞中发现了心肌MCC的超微结构变化。注意到在肺动脉分支栓塞时,左心室心肌后部和右心室前壁相对于冠状动脉供血不足的易损性。

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