Unité de Recherche Clinique, Neuilly sur Marne, France.
Eur J Pain. 2013 Oct;17(9):1385-92. doi: 10.1002/j.1532-2149.2013.00310.x. Epub 2013 Mar 25.
Schizophrenia patients display impaired recognition of their own emotions and those of others and deficits in several domains of empathy. The first-person experience of pain and observing others in pain normally trigger strong emotional mechanisms. We therefore hypothesized that schizophrenia patients would display impaired recognition and categorization of both their own pain and the pain of others.
We studied 29 patients (18 men/11 women; 36 ± 13 years old) with paranoid schizophrenia-spectrum disorder and 27 healthy volunteers (20 men/7 women; 31 ± 9 years old) matched for age, gender, IQ and socio-cultural level. We assessed symptom severity and theory of mind. The participants' ability to detect and categorize pain in others was assessed with the sensitivity to expressions of pain (STEP) test, which is based on facial expressions, and another dynamic test involving a series of video sequences showing various pain-inducing events. The ability of patients to evaluate their own pain was assessed with the situational pain questionnaire (SPQ), which includes a series of questions assessing how one would expect to feel in different imaginary situations. Empathic tendencies were assessed with the interpersonal reactivity index.
Patients and controls differed significantly in STEP, pain video and SPQ scores. By contrast with control subjects, the patients' pain judgements were not correlated with their affective or cognitive empathic capacities.
Schizophrenic patients have a deficit of the identification and categorization of pain both in themselves and in others.
精神分裂症患者在识别自身和他人的情绪以及同理心的几个领域存在缺陷。对疼痛的第一人称体验和观察他人的疼痛通常会引发强烈的情感机制。因此，我们假设精神分裂症患者在识别和分类自身疼痛和他人疼痛时会出现障碍。
我们研究了 29 名（18 名男性/11 名女性；36 ± 13 岁）偏执型精神分裂症谱系障碍患者和 27 名健康志愿者（20 名男性/7 名女性；31 ± 9 岁），他们在年龄、性别、智商和社会文化水平上相匹配。我们评估了症状严重程度和心理理论。通过基于面部表情的疼痛表情敏感性测试（STEP）和涉及一系列显示各种疼痛诱发事件的视频序列的另一个动态测试，评估参与者识别和分类他人疼痛的能力。患者评估自身疼痛的能力通过情境疼痛问卷（SPQ）进行评估，该问卷包括一系列问题，评估在不同想象情况下的感受。同理心倾向通过人际反应指数进行评估。
患者和对照组在 STEP、疼痛视频和 SPQ 评分上存在显著差异。与对照组相比，患者的疼痛判断与他们的情感或认知同理心能力无关。
精神分裂症患者在识别和分类自身和他人的疼痛方面存在缺陷。
