Otake S, Banno T, Ohba S, Noda M, Yamamoto M
Department of Radiology, Nagoya City University Medical School, Aichi, Japan.
Radiology. 1990 Jul;176(1):145-8. doi: 10.1148/radiology.176.1.2353084.
Twelve patients with muscular sarcoidosis were evaluated with magnetic resonance (MR) imaging: Nine patients had the nodular type and three had the myopathic type of muscular sarcoidosis. The nodular type showed a characteristic appearance on MR images. In each patient with the nodular type, both T1- and T2-weighted axial spin-echo images showed an oval nodule consisting of a star-shaped area of low signal intensity surrounded by an area of high signal intensity. Histopathologic correlation in patients with the nodular type revealed that the central portion of the nodule was fibrotic tissue surrounded by inflammatory granulomatous tissue. In each patient with the myopathic type of muscular sarcoidosis, MR images failed to show any abnormality; the authors hypothesize that this failure correlated with the sparse distribution of epithelioid cell granulomas. Identification of the star-shaped area of low signal intensity may help in the diagnosis of muscular sarcoidosis and the differentiation of lesions associated with sarcoidosis from other soft-tissue masses.
对12例肌肉结节病患者进行了磁共振(MR)成像评估:9例为结节型,3例为肌病型肌肉结节病。结节型在MR图像上表现出特征性外观。在每例结节型患者中,T1加权和T2加权轴向自旋回波图像均显示一个椭圆形结节,由低信号强度的星形区域被高信号强度区域包围组成。结节型患者的组织病理学相关性显示,结节的中央部分是由炎性肉芽肿组织包围的纤维化组织。在每例肌病型肌肉结节病患者中,MR图像未显示任何异常;作者推测这种情况与上皮样细胞肉芽肿的稀疏分布有关。识别低信号强度的星形区域可能有助于肌肉结节病的诊断以及将结节病相关病变与其他软组织肿块区分开来。