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犬炎性肠病:诊断与管理的当前及潜在生物标志物

Canine inflammatory bowel disease: current and prospective biomarkers for diagnosis and management.

作者信息

Collins Mickila T

机构信息

Animal Specialty Group, Los Angeles, CA, USA.

出版信息

Compend Contin Educ Vet. 2013 Mar;35(3):E5.

Abstract

Inflammatory bowel disease (IBD) is a common gastrointestinal disorder of dogs. Current management strategies for this disease typically involve assessing the patient for resolution of clinical signs. Biologic markers that can be used to objectively assess the natural progression and predict the course of clinical disease, including response to treatment, are needed. Over the past 5 to 10 years, there has been an ongoing search for a cost-effective, minimally invasive laboratory parameter that can detect disease activity and aid in monitoring treatment. This article reviews the biomarkers currently available for evaluating dogs with IBD.

摘要

炎症性肠病(IBD)是犬类常见的胃肠道疾病。目前针对该疾病的管理策略通常包括评估患者临床症状的缓解情况。需要能够客观评估疾病自然进展并预测临床疾病进程(包括对治疗的反应)的生物标志物。在过去5到10年里,人们一直在寻找一种经济高效、微创的实验室参数,以检测疾病活动并辅助监测治疗。本文综述了目前可用于评估患IBD犬的生物标志物。

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