Simpson Kenneth W, Jergens Albert E
Veterinary Clinical Sciences, College of Veterinary Medicine, Cornell University, VMC2001, Ithaca, NY 14853, USA.
Vet Clin North Am Small Anim Pract. 2011 Mar;41(2):381-98. doi: 10.1016/j.cvsm.2011.02.003.
Inflammatory bowel disease (IBD) is the collective term for a group of chronic enteropathies characterized by persistent or recurrent gastrointestinal (GI) signs and inflammation of the GI tract. The specific steps that lead to IBD and the basis for phenotypic variation and unpredictable responses to treatment are not known. This article examines IBD in dogs, focusing on the interaction between genetic susceptibility and the enteric microenvironment (bacteria, diet), the utility of recently developed histologic criteria, the prognostic indicators, and the standardized approaches to treatment.
炎症性肠病（IBD）是一组慢性肠病的统称，其特征为持续或反复出现的胃肠道（GI）症状以及胃肠道炎症。导致IBD的确切步骤、表型变异的基础以及对治疗不可预测反应的原因尚不清楚。本文探讨犬类的IBD，重点关注遗传易感性与肠道微环境（细菌、饮食）之间的相互作用、最近制定的组织学标准的实用性、预后指标以及标准化的治疗方法。
