Itoga Masamichi, Ito Wataru, Ueki Shigeharu, Takeda Masahide, Moritoki Yuki, Kobayashi Yoshiki, Chihara Mami, Suzuki Naoshi, Sasaki Hideto, Chihara Junichi
Department of Infection, Allergy, Clinical Immunology and Laboratory Medicine, Akita University Graduate School of Medicine, 1-1-1, Hondo, Akita 010-8543, Japan.
Case Rep Med. 2013;2013:496304. doi: 10.1155/2013/496304. Epub 2013 Mar 5.
Pulmonary metastasis from leiomyosarcoma is rare and its clinical management is challenging. A single lung metastasis from a perineal leiomyosarcoma occurred in a 79-year-old woman. Five months after resection of the lung metastasis, a new metastatic tumor developed in the contralateral lung. Since the patient did not desire to receive hospitalized treatment, TS-1 (an oral agent consisting of a combination of tegafur, gimeracil, and oteracil potassium) therapy was started on an outpatient basis. The lung metastasis has been successfully controlled for at least 17 months with excellent tolerability. The clinical features and the treatment of this case are discussed.
平滑肌肉瘤的肺转移罕见，其临床管理具有挑战性。一名79岁女性发生了会阴部平滑肌肉瘤的单发性肺转移。肺转移瘤切除术后五个月，对侧肺出现了新的转移瘤。由于患者不希望接受住院治疗，遂开始在门诊给予替吉奥（一种由替加氟、吉美嘧啶和奥替拉西钾组成的口服制剂）治疗。肺转移已成功控制至少17个月且耐受性良好。本文讨论了该病例的临床特征及治疗情况。
