γ-谷氨酰转肽酶、甘油三酯与酶诱导作用
Gamma-glutamyl transpeptidase, triglycerides, and enzyme induction.
作者信息
Martin P J, Martin J V, Goldberg D M
出版信息
Br Med J. 1975 Jan 4;1(5948):17-8. doi: 10.1136/bmj.1.5948.17.
Abstract
A study conducted on 109 consecutive patients submitted for routine lipid and lipoprotein screening has shown a significant positive association between serum gamma-glutamyl transpeptidase (gamma-GT) activity and the serum triglyceride concentration and between serum gamma-GT activity and the serum pre-beta-lipoprotein concentration. We suggest that these associations may reflect hepatic microsomal enzyme induction in hyperlipidaemic subjects which increases the hepatic content of the rate-limiting enzyme(s) for triglyceride synthesis.
摘要
对109例连续接受常规血脂和脂蛋白筛查的患者进行的一项研究表明，血清γ-谷氨酰转肽酶（γ-GT）活性与血清甘油三酯浓度之间以及血清γ-GT活性与血清前β-脂蛋白浓度之间存在显著正相关。我们认为，这些关联可能反映了高脂血症患者肝微粒体酶的诱导，这增加了甘油三酯合成限速酶的肝脏含量。
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本文引用的文献
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