人类嗜T淋巴细胞病毒1型（HTLV-1）分离株MT-2的包膜基因序列及其与其他HTLV-1分离株的比较。
Envelope gene sequence of HTLV-1 isolate MT-2 and its comparison with other HTLV-1 isolates.
作者信息
Gray G S, White M, Bartman T, Mann D
机构信息
Repligen Corporation, Cambridge, Massachusetts 02139.
出版信息
Virology. 1990 Jul;177(1):391-5. doi: 10.1016/0042-6822(90)90498-g.
The DNA sequence of the envelope gene of the HTLV-1 proviral clone MT-2 was determined and compared with envelope sequences of other HTLV-1 isolates. The comparison of this sequence with another of Japanese origin and two of Caribbean origin does not support the proposal by K.T.A. Malik, J. Even, and A. Karpas (J. Gen. Virol. 69, 1695-1710, 1988) that isolates of similar geographic origins are more homologous than isolates of different origins. No significant differences in the degree of homology could be found among the HTLV-1 envelope gene sequences from Japanese and Caribbean isolates. The comparison confirms the high degree of homology previously found between various HTLV-1 isolates (greater than 97%).
测定了HTLV-1前病毒克隆MT-2包膜基因的DNA序列，并与其他HTLV-1分离株的包膜序列进行了比较。将该序列与另一个日本来源和两个加勒比来源的序列进行比较，并不支持K.T.A. Malik、J. Even和A. Karpas（《病毒学杂志》69，1695 - 1710，1988年）提出的相似地理来源的分离株比不同来源的分离株具有更高同源性的观点。在日本和加勒比分离株的HTLV-1包膜基因序列之间未发现同源程度的显著差异。该比较证实了先前在各种HTLV-1分离株之间发现的高度同源性（大于97%）。
Zotero 插件