Suppr超能文献

纳米制药专利的趋势。

Trends in nanopharmaceutical patents.

作者信息

Antunes Adelaide, Fierro Iolanda, Guerrante Rafaela, Mendes Flavia, de M Alencar Maria Simone

机构信息

National Institute of Industrial Property (Brazil), Mayrink Veiga, n° 9 Centro, Rio de Janeiro, Brazil.

出版信息

Int J Mol Sci. 2013 Mar 27;14(4):7016-31. doi: 10.3390/ijms14047016.

Abstract

Investment in nanotechnology is now a given constant by governments, research centers and companies in both more developed countries and emerging markets. Due to their characteristics, such as high stability, ability to enable antigen identification on specific cells in the human body and controlling the release of drugs and, therefore, improving therapies, nanoparticles have been the subject of research and patent applications in the pharmaceutical field. According to the Organization for Economic Co-operation and Development (OCDE), patent data can be used as a source of information in order to measure science and technology activities. Thereby, this paper presents an analysis based on patent documents related to nanotechnology in the pharmaceutical sector. As a result, the analysis of patents demonstrate primarily that nanobiotechnology attracts high levels of R&D investments, including nanoparticle-based chemotherapeutic agents/drugs, monoclonal antibody nanoparticle complexes and their role in drug delivery or contrast agents with non-toxic effects.

摘要

目前,无论是在更发达的国家还是新兴市场,政府、研究中心和企业对纳米技术的投资都是一种既定的常态。由于纳米颗粒具有诸如高稳定性、能够在人体特定细胞上实现抗原识别以及控制药物释放从而改善治疗效果等特性,它们一直是制药领域研究和专利申请的主题。根据经济合作与发展组织(OCDE)的说法,专利数据可作为衡量科技活动的信息来源。因此,本文对制药领域中与纳米技术相关的专利文件进行了分析。结果表明,专利分析主要显示纳米生物技术吸引了大量的研发投资,包括基于纳米颗粒的化疗药物、单克隆抗体纳米颗粒复合物及其在药物递送中的作用或具有无毒作用的造影剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69b5/3645674/9734d54bf632/ijms-14-07016f1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验