纳米技术在人类医疗保健中的现状与未来。

The present and future of nanotechnology in human health care.

作者信息

Sahoo S K, Parveen S, Panda J J

机构信息

Institute of Life Sciences, Nanomedicine Laboratory, Chandrasekharpur, Bhubaneswar, Orissa, India.

出版信息

Nanomedicine. 2007 Mar;3(1):20-31. doi: 10.1016/j.nano.2006.11.008.

DOI:10.1016/j.nano.2006.11.008

PMID:17379166

Abstract

Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices derived from engineering, physics, chemistry, and biology. The burgeoning new field of nanotechnology, opened up by rapid advances in science and technology, creates myriad new opportunities for advancing medical science and disease treatment in human health care. Applications of nanotechnology to medicine and physiology imply materials and devices designed to interact with the body at subcellular (i.e., molecular) scales with a high degree of specificity. This can be potentially translated into targeted cellular and tissue-specific clinical applications designed to achieve maximal therapeutic efficacy with minimal side effects. In this review the chief scientific and technical aspects of nanotechnology are introduced, and some of its potential clinical applications are discussed.

摘要

纳米技术是一个多学科领域，涵盖了源自工程学、物理学、化学和生物学的大量各种各样的设备。由科技的迅速发展所开创的新兴纳米技术领域，为推进医学科学以及人类医疗保健中的疾病治疗创造了无数新机会。纳米技术在医学和生理学中的应用意味着设计用于在亚细胞（即分子）尺度上与身体进行高度特异性相互作用的材料和设备。这有可能转化为旨在以最小副作用实现最大治疗效果的靶向细胞和组织特异性临床应用。在这篇综述中，介绍了纳米技术的主要科学和技术方面，并讨论了其一些潜在的临床应用。