Wahl R U, Megahed M
Klinik für Allergologie und Dermatologie, Universitätsklinikum RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Hautarzt. 2013 May;64(5):334-6. doi: 10.1007/s00105-013-2551-z.
A 73-year-old man has been suffering from a pulmonary adenocarcinoma for three years. He has been treated with the EGF-inhibitor erlotinib for the past 18 months. While taking this medication he developed a progressive papulopustular rash on his face and trunk which later spread to his thighs. Topical treatment with methylprednisolone and nadifloxacin, as well as short courses of systemic doxycycline and ciprofloxacin, led to marked improvement and control of his skin condition.
一名73岁男性患肺腺癌已三年。在过去18个月里，他一直接受表皮生长因子抑制剂厄洛替尼治疗。服用此药期间，他面部和躯干出现进行性丘疹脓疱性皮疹，后来蔓延至大腿。局部使用甲泼尼龙和那氟沙星，以及短期口服强力霉素和环丙沙星，使他的皮肤状况得到显著改善和控制。
