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全球分析与药品集出版相关的因素

Worldwide analysis of factors associated with medicines compendia publishing.

机构信息

Pharmacoepidemiology and Social Pharmacy Unit, Research Institute for Medicines and Pharmaceutical Sciences, University of Lisbon, Lisbon, Portugal.

出版信息

Int J Clin Pharm. 2013 Jun;35(3):386-92. doi: 10.1007/s11096-012-9744-x. Epub 2013 Mar 28.

DOI:10.1007/s11096-012-9744-x
PMID:23536106
Abstract

BACKGROUND

Medicines compendia, also called formularies, are the most commonly used drug information source among health care professionals.

OBJECTIVE

The aim was to identify the countries publishing medicines compendia and the socio-demographic factors associated to this fact. Additionally, we sought to determine the use of foreign compendia in countries lacking their own.

SETTING

Global web-based survey.

METHOD

Healthcare practitioners and researchers from 193 countries worldwide were invited to complete a web-based survey. The questionnaire investigated the existence of a national compendium, or the use of foreign compendia in the absence of one. Demographic and socioeconomic variables were used to predict compendia publishing through a multivariate analysis.

MAIN OUTCOME MEASURE

Existence of national medicines compendia and foreign compendia used.

RESULTS

Professionals from 132 countries completed the survey (response rate at a country level 68.4%, comprising 90.9% global population). Eighty-four countries (63.6%) reported publishing a medicines compendium. In the multivariate analysis, only two covariates had significant association with compendia publishing. Being a member of the Organisation for the Economic Cooperation and Development was the only variable positively associated with compendia publishing (OR = 37.5; 95% CI = 2.3:599.8). In contrast, the countries that listed French as an official language were less likely to publish a compendium (OR = 0.07; 95% CI = 0.007:0.585). Countries without national compendia reported using the British National Formulary most commonly, followed by the Dictionnaire Vidal.

CONCLUSION

Publication of medicines compendia is associated with socio-economic development. Countries lacking a national compendium, use foreign compendia from higher-income countries. Creating an international medicines compendium under the leadership of the World Health Organisation, rather than merely a 'model', would reduce the risks of using information sources not-adapted to the necessities of developing countries.

摘要

背景

药品手册,也称为处方集,是医疗保健专业人员最常使用的药物信息来源。

目的

确定出版药品手册的国家以及与这一事实相关的社会人口因素。此外,我们还试图确定在没有本国手册的国家使用外国手册的情况。

设置

全球基于网络的调查。

方法

邀请来自全球 193 个国家的医疗保健从业者和研究人员完成基于网络的调查。调查问卷调查了是否存在国家手册,或者在没有国家手册的情况下是否使用外国手册。使用人口统计学和社会经济变量通过多变量分析预测手册出版。

主要观察结果

国家药品手册的存在和外国手册的使用情况。

结果

来自 132 个国家的专业人员完成了调查(国家一级的回应率为 68.4%,占全球人口的 90.9%)。84 个国家(63.6%)报告出版了药品手册。在多变量分析中,只有两个协变量与手册出版有显著关联。作为经济合作与发展组织的成员是与手册出版唯一正相关的变量(OR = 37.5;95% CI = 2.3:599.8)。相比之下,将法语列为官方语言的国家出版手册的可能性较小(OR = 0.07;95% CI = 0.007:0.585)。没有国家手册的国家最常使用英国国家处方集,其次是维达尔字典。

结论

药品手册的出版与社会经济发展有关。缺乏国家手册的国家使用来自高收入国家的外国手册。在世界卫生组织的领导下创建一个国际药品手册,而不仅仅是一个“模式”,将降低使用不适合发展中国家需求的信息源的风险。

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