Baĭbekova E M, Sultanova L I
Arkh Anat Gistol Embriol. 1990 Feb;98(2):88-94.
As a result of the experimental investigation of the liver damaged with CCL4, its essential structural changes have been revealed. They resemble those specific for a chronic toxic hepatitis. Administration of potassium orothate (100 mg/kg) increases proliferative activity of hepatocytes without any essential influence on intracellular regeneration. Under conditions of a delayed differentiation and lack of resorption of an abundantly outgrowing connective tissue, this results in a more profound pathological process in the liver. Benzonal administration (50 mg/kg) facilitates structural normalization of the chronically damaged liver, owing to activation of both cellular and intracellular regeneration.
通过对四氯化碳损伤肝脏的实验研究，揭示了其基本结构变化。这些变化类似于慢性中毒性肝炎的特异性变化。服用乳清酸钾（100毫克/千克）可增加肝细胞的增殖活性，而对细胞内再生无任何实质性影响。在分化延迟和大量增生的结缔组织吸收不足的情况下，这会导致肝脏中更严重的病理过程。服用苯佐那酯（50毫克/千克）有助于慢性损伤肝脏的结构正常化，这是由于细胞和细胞内再生均被激活。
