Posokhova E A
Biull Eksp Biol Med. 1981;91(1):76-8.
Experiments on 50 albino rats with liver dystrophy caused by carbon tetrachloride have shown that orotic acid calcium pangamate and lipamide decrease the damage to subcellular structures of hepatocytes, favour normalization of cytoplasmatic cell components. Combined use of orotic acid and calcium pangamate was found to promote more positive effect on membranous constituents and hyperplastic processes in liver parenchymal cells as compared with the effect that might be attained by applications of the drugs alone. The combined use of the drugs is also conducive to more intensive intracellular reparative regeneration.
对50只由四氯化碳引起肝营养不良的白化大鼠进行的实验表明，乳清酸氨基乙酸钙和硫辛酸可减少对肝细胞亚细胞结构的损伤，有助于细胞质细胞成分正常化。与单独使用药物相比，发现乳清酸和氨基乙酸钙联合使用对肝实质细胞膜成分和增生过程具有更积极的作用。药物联合使用还有利于更强烈的细胞内修复性再生。
