Kavtiashvili K G, Gabuniia U A, Khundadze T O, Dugladze D I, Chumburidze R A, Khananashvili Sh D
Arkh Patol. 1990;52(2):47-52.
The efficiency of the newborn allogenic hepatocytes (NAH) in the treatment of the acute liver failure (ALF) in dogs is studied histologically, histochemically and ultrastructurally. The administration of NAH prevents, in part, the ischemic cell death and is efficient in the stimulation of the liver regeneration in ALF. NAH enhance hepatocyte and Kupffer cell proliferation, reduce the number of degenerative and necrotic foci, increase the number of cell organelles, their volume, compensate the function of the damaged liver, facilitate the morpho-functional restoration of the recipient ischemically damaged liver.
通过组织学、组织化学和超微结构研究了新生同种异体肝细胞（NAH）治疗犬急性肝衰竭（ALF）的效率。NAH的给药部分预防了缺血性细胞死亡，并且在刺激ALF中的肝脏再生方面是有效的。NAH增强肝细胞和库普弗细胞增殖，减少变性和坏死灶数量，增加细胞器数量及其体积，补偿受损肝脏的功能，促进受体缺血性损伤肝脏的形态功能恢复。
