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Navigating the B(12) road: assimilation, delivery, and disorders of cobalamin.探索 B(12)之路：钴胺素的吸收、递送和代谢紊乱。
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Redox-Linked Coordination Chemistry Directs Vitamin B Trafficking.氧化还原相关配位化学指导维生素 B 转运。
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Biochemistry of B12-cofactors in human metabolism.人体新陈代谢中维生素B12辅助因子的生物化学
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Cobalt: its role in health and disease.钴：其在健康与疾病中的作用。
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Vitamin B12-derivatives-enzyme cofactors and ligands of proteins and nucleic acids.维生素 B12 衍生物——酶的辅助因子和蛋白质及核酸的配体。
Chem Soc Rev. 2011 Aug;40(8):4346-63. doi: 10.1039/c1cs15118e. Epub 2011 Jun 20.
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B12 trafficking in mammals: A for coenzyme escort service.哺乳动物中的维生素B12转运：辅酶护送服务之所需
ACS Chem Biol. 2006 Apr 25;1(3):149-59. doi: 10.1021/cb6001174.
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Structure-based perspectives on B12-dependent enzymes.基于结构视角对依赖维生素B12的酶的研究
Annu Rev Biochem. 1997;66:269-313. doi: 10.1146/annurev.biochem.66.1.269.
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Coenzyme B12 (cobalamin)-dependent enzymes.辅酶B12（钴胺素）依赖性酶。
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Naturally occurring cobalamin (B) analogs can function as cofactors for human methylmalonyl-CoA mutase.天然存在的钴胺素（B）类似物可以作为人甲基丙二酰辅酶 A 变位酶的辅助因子。
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Molecular basis for dysfunction of some mutant forms of methylmalonyl-CoA mutase: deductions from the structure of methionine synthase.甲基丙二酰辅酶A变位酶某些突变形式功能障碍的分子基础：从甲硫氨酸合酶结构推导而来。
Proc Natl Acad Sci U S A. 1996 May 28;93(11):5550-5. doi: 10.1073/pnas.93.11.5550.
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The common homocystinuria-associated P1173L variant of human methionine synthase impairs reductive methylation.人类甲硫氨酸合酶常见的同型胱氨酸尿症相关P1173L变体损害还原甲基化作用。
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Transporters in vitamin uptake and cellular metabolism: impacts on health and disease.维生素摄取与细胞代谢中的转运蛋白：对健康和疾病的影响。
Life Metab. 2025 Mar 10;4(3):loaf008. doi: 10.1093/lifemeta/loaf008. eCollection 2025 Jun.
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Bacterial Metallostasis: Metal Sensing, Metalloproteome Remodeling, and Metal Trafficking.细菌金属稳态：金属感应、金属蛋白质组重塑及金属转运
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Brain-gut-brain axis, nutrition, and autism spectrum disorders: a review.脑-肠-脑轴、营养与自闭症谱系障碍：综述
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Vitamin B Metabolism: A Network of Multi-Protein Mediated Processes.维生素 B 代谢：一个多蛋白介导的过程网络。
Int J Mol Sci. 2024 Jul 23;25(15):8021. doi: 10.3390/ijms25158021.
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A Noble Metal Substitution Leads to B Cofactor Mimicry by a Rhodibalamin.一种贵金属取代导致了 Rhodibalamin 对 B 辅因子的模拟。
Biochemistry. 2024 Aug 6;63(15):1955-1962. doi: 10.1021/acs.biochem.4c00216. Epub 2024 Jul 16.
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Nutrient smuggling: Commensal gut bacteria-derived extracellular vesicles scavenge vitamin B12 and related cobamides for microbe and host acquisition.营养物质走私：共生肠道细菌衍生的细胞外囊泡清除维生素B12及相关钴胺素以供微生物和宿主获取。
J Extracell Biol. 2022 Oct 11;1(10):e61. doi: 10.1002/jex2.61. eCollection 2022 Oct.
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Exploring the Impact of Cigarette Smoke Extracts on Vitamin B: Insights into the Transformation of Methylcobalamin and Hydroxycobalamin to Cyanocobalamin through Evaluation.探索香烟烟雾提取物对维生素B的影响：通过评估深入了解甲钴胺和羟钴胺向氰钴胺的转化
Biochem Res Int. 2024 Apr 18;2024:8827402. doi: 10.1155/2024/8827402. eCollection 2024.
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Cobalt-Sulfur Coordination Chemistry Drives B Loading onto Methionine Synthase.钴 - 硫配位化学驱动钴胺素加载到蛋氨酸合酶上。
J Am Chem Soc. 2023 Nov 2. doi: 10.1021/jacs.3c07941.
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Novel CSF biomarkers for diagnosis and integrated analysis of neuropsychiatric systemic lupus erythematosus: based on antibody profiling.用于神经精神性系统性红斑狼疮诊断和综合分析的新型 CSF 生物标志物：基于抗体谱分析。
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本文引用的文献
1
The C-terminal domain of CblD interacts with CblC and influences intracellular cobalamin partitioning.CblD 的 C 末端结构域与 CblC 相互作用，并影响细胞内钴胺素的分配。
Biochimie. 2013 May;95(5):1023-32. doi: 10.1016/j.biochi.2013.02.003. Epub 2013 Feb 14.
2
Nitrogenase assembly.固氮酶组装
Biochim Biophys Acta. 2013 Aug-Sep;1827(8-9):1112-22. doi: 10.1016/j.bbabio.2012.12.001. Epub 2012 Dec 8.
3
High resolution melting analysis of the MMAA gene in patients with cblA and in those with undiagnosed methylmalonic aciduria.高分辨率熔解分析 cblA 患者和未确诊的甲基丙二酸尿症患者的 MMAA 基因。
Mol Genet Metab. 2012 Nov;107(3):363-7. doi: 10.1016/j.ymgme.2012.09.012. Epub 2012 Sep 15.
4
Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism.ABCD4 基因突变导致一种新的维生素 B12 代谢先天性错误。
Nat Genet. 2012 Oct;44(10):1152-5. doi: 10.1038/ng.2386. Epub 2012 Aug 26.
5
Structural features of recombinant MMADHC isoforms and their interactions with MMACHC, proteins of mammalian vitamin B12 metabolism.重组 MMADHC 同工型的结构特征及其与 MMACHC 蛋白（哺乳动物维生素 B12 代谢蛋白）的相互作用。
Mol Genet Metab. 2012 Nov;107(3):352-62. doi: 10.1016/j.ymgme.2012.07.001. Epub 2012 Jul 11.
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Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function.MMACHC 结构揭示了其 B12 处理功能的一个富含精氨酸的口袋和一个结构域交换二聚体。
Biochemistry. 2012 Jun 26;51(25):5083-90. doi: 10.1021/bi300150y. Epub 2012 Jun 14.
7
Molecular mechanisms leading to three different phenotypes in the cblD defect of intracellular cobalamin metabolism.导致细胞内钴胺素代谢 cblD 缺陷出现三种不同表型的分子机制。
Hum Mol Genet. 2012 Mar 15;21(6):1410-8. doi: 10.1093/hmg/ddr579. Epub 2011 Dec 8.
8
Structural basis of multifunctionality in a vitamin B12-processing enzyme.维生素 B12 加工酶多功能性的结构基础。
J Biol Chem. 2011 Aug 26;286(34):29780-7. doi: 10.1074/jbc.M111.261370. Epub 2011 Jun 22.
9
Zinc homeostasis and signaling in health and diseases: Zinc signaling.锌的体内平衡和信号转导在健康和疾病中的作用：锌信号转导。
J Biol Inorg Chem. 2011 Oct;16(7):1123-34. doi: 10.1007/s00775-011-0797-4. Epub 2011 Jun 10.
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Loss of allostery and coenzyme B12 delivery by a pathogenic mutation in adenosyltransferase.腺苷转移酶的致病性突变导致别构和辅酶 B12 传递丧失。
Biochemistry. 2011 Jun 28;50(25):5790-8. doi: 10.1021/bi2006306. Epub 2011 Jun 2.
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