State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China.
Org Lett. 2013 Apr 19;15(8):1978-81. doi: 10.1021/ol400645v. Epub 2013 Mar 29.
A concise and scalable synthesis of a cis-fused bicyclo[5.3.0]decane ring system has been developed for the total synthesis of echinopines. The core of the natural products was constructed efficiently through an intramolecular 1,3-dipolar cycloaddition and ring contraction strategy.
已经开发出一种简洁且可扩展的顺式稠合双环[5.3.0]癸烷环系合成方法，用于海罂粟碱类天然产物的全合成。通过分子内 1,3-偶极环加成和环收缩策略，有效地构建了天然产物的核心。
