Henan Center for Animal Disease Control and Prevention, Animal Husbandry Bureau of Henan Province, Zhengzhou, 450008, Henan Province, People's Republic of China.
Arch Virol. 2013 Sep;158(9):1973-8. doi: 10.1007/s00705-013-1682-y. Epub 2013 Mar 31.
We report the complete nucleotide sequence of a reassortant infectious bursal disease (IBD) virus (IBDV) HN isolate from commercial broiler flocks in central China. The genome consisted of 3,232 and 2,652 nucleotides in the coding regions of segments A and B, respectively. Alignment of both nucleotide and deduced amino acid sequences and phylogenetic analysis revealed that the genome segments A and B of HN were derived from the attenuated strain B87 and the VV strain OKYM. This is a new reassortant IBDV strain that has emerged in nature, involving segment A of a cell-culture-adapted attenuated vaccine strain B87.
我们报告了一种源自中国中部商业肉鸡群的重组传染性法氏囊病(IBD)病毒(IBDV)HN 分离株的完整核苷酸序列。该基因组在编码区分别由 3232 和 2652 个核苷酸组成。核苷酸和推导的氨基酸序列的比对以及系统发育分析表明,HN 的基因组片段 A 和 B 分别来自于减毒疫苗株 B87 和 VV 株 OKYM。这是一种新的自然出现的重组 IBDV 株,涉及细胞培养适应的减毒疫苗株 B87 的片段 A。