Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Ups J Med Sci. 2013 May;118(2):130-3. doi: 10.3109/03009734.2013.786000. Epub 2013 Apr 2.
We here report a case of diabetic ketoacidosis at onset of type 1 diabetes after a prolonged period of starvation due to anorexia nervosa. A 53-year-old female with a history of anorexia nervosa was admitted to the psychiatric clinic due to psychotic behaviour and inability to take care of herself. Twenty-four hours after admission she was transferred to the clinic of internal medicine due to altered mental status, and laboratory screening revealed a pH of 6.895 and blood glucose concentration of 40 mmol/L. Due to the unusual combination of prolonged starvation and diabetic ketoacidosis we implemented some modifications of existing treatment guidelines and some special considerations regarding nutrition in order to prevent a re-feeding syndrome.
我们在此报告一例 1 型糖尿病患者在神经性厌食症导致长时间饥饿后出现糖尿病酮症酸中毒。一名 53 岁女性,既往有神经性厌食症病史,因精神病行为和无法自理而被收入精神科病房。入院 24 小时后,因精神状态改变转入内科病房,实验室筛查显示 pH 值为 6.895,血糖浓度为 40mmol/L。由于长时间饥饿和糖尿病酮症酸中毒的罕见组合,我们对现有的治疗指南进行了一些修改,并对营养方面进行了一些特殊考虑,以防止再喂养综合征。