Eshraghian Ahad, Kamyab Amir A'lam
Department of Internal Medicine, Shiraz University of Medical Sciences, Iran.
Intern Med. 2013;52(7):823-5. doi: 10.2169/internalmedicine.52.9272. Epub 2013 Apr 1.
Atorvastatin is a lipid lowering agent that is widely used worldwide. Rhabdomyolysis is a rare but serious side effect that may lead to renal failure and dangerous electrolyte abnormalities in patients with decreased hepatic clearance of atorvastatin. We herein report the case of a patient with liver cirrhosis receiving atorvastatin therapy for ischemic heart disease and hyperlipidemia who developed rhabdomyolysis and acute renal failure.
阿托伐他汀是一种降脂药物，在全球范围内广泛使用。横纹肌溶解是一种罕见但严重的副作用，在阿托伐他汀肝清除率降低的患者中可能导致肾衰竭和危险的电解质异常。我们在此报告一例肝硬化患者，该患者因缺血性心脏病和高脂血症接受阿托伐他汀治疗，发生了横纹肌溶解和急性肾衰竭。
