Williams E C
Department of Hematology, University of Wisconsin, Madison.
Clin Cardiol. 1990 Apr;13(4 Suppl 6):VI34-6.
The use of indwelling central catheters for administration of chemotherapy, blood products, and parenteral nutrition is becoming increasingly common. Thrombosis, manifested as formation of either a fibrin sleeve around the catheter or a thrombus adherent to the vessel wall, is a major complication of the use of such catheters. Although frequently asymptomatic, thrombosis may cause catheter occlusion, vascular obstruction, septic phlebitis, or pulmonary embolism. The pathophysiology and management of catheter thrombosis are discussed.
留置中心静脉导管用于化疗药物、血液制品及肠外营养的输注正变得越来越普遍。血栓形成，表现为围绕导管形成纤维蛋白套或血栓附着于血管壁，是使用此类导管的主要并发症。尽管血栓形成通常无症状，但可能导致导管堵塞、血管阻塞、脓毒性静脉炎或肺栓塞。本文讨论了导管血栓形成的病理生理学及处理方法。
