Department of Radiology, University of Ulsan College of Medicine, Seoul, Korea.
J Thorac Imaging. 2013 May;28(3):160-70. doi: 10.1097/RTI.0b013e31828d4087.
Pulmonary emphysema is a pathologic condition characterized by permanently enlarged airspaces distal to the terminal bronchiole with destruction of the alveolar walls. Functional information of the lungs is important to understand the pathophysiology of emphysema and that of chronic obstructive pulmonary disease. With the recent developments in magnetic resonance imaging (MRI) techniques, functional MRI with variable MR sequences can be used for the evaluation of different physiological and anatomic changes seen in cases of pulmonary emphysema. In this review article, we will focus on a brief description of each method, results of some of the most recent work, and the clinical application of such knowledge.
肺气肿是一种病理状态，其特征是终末细支气管远端的气腔永久性扩张，肺泡壁破坏。了解肺部的功能信息对于理解肺气肿和慢性阻塞性肺疾病的病理生理学非常重要。随着磁共振成像（MRI）技术的最新发展，可变的 MRI 序列的功能 MRI 可用于评估肺气肿病例中出现的不同生理和解剖变化。在这篇综述文章中，我们将重点简要描述每种方法、一些最新研究的结果以及这些知识的临床应用。
