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睡眠与自杀:对 39.4 万名台湾成年人队列的分析。

Sleep and suicide: an analysis of a cohort of 394,000 Taiwanese adults.

机构信息

School of Social and Community Medicine, University of Bristol, Bristol, UK.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2013 Sep;48(9):1457-65. doi: 10.1007/s00127-013-0675-1. Epub 2013 Apr 2.

Abstract

BACKGROUND

Sleep problems may lead to, or be symptomatic of, depression and other mental illnesses yet few studies have investigated their association with suicide risk.

DESIGN

Prospective cohort study.

SETTING

Taiwan.

PARTICIPANTS

393,983 men and women aged 20 or above participating in the MJ health check-up programme.

RESULTS

There were 335 suicides over a mean of 7.4 years follow-up. There was a reverse J-shaped association between sleep duration and suicide risk. When compared with those sleeping 6-8 h per night the adjusted hazard ratios (95% confidence intervals) for suicide associated with 0-4, 4-6 and >8 h sleep were 3.5 (2.0-6.1), 1.5 (1.1-1.9) and 1.5 (1.1-2.0), respectively. People requiring sleeping pills to get to sleep (1.2% participants) were at over 11-fold increased risk; difficulty falling asleep (11.5% participants), frequent dreaming (16.7%) and being easily awoken (30.6%) were associated with a 2.0-, 1.6- and 1.3-fold increased risk of suicide, respectively.

CONCLUSIONS

Less than 6 h sleep duration, sleep disturbances and reported use of sleep medicines are markers of suicide risk. Sleep problems should be assessed when evaluating suicide risk.

摘要

背景

睡眠问题可能导致抑郁和其他精神疾病,或者是这些疾病的症状,但很少有研究调查它们与自杀风险的关系。

设计

前瞻性队列研究。

地点

中国台湾。

参与者

393983 名年龄在 20 岁及以上参加 MJ 健康检查计划的男性和女性。

结果

在平均 7.4 年的随访中,有 335 人自杀。睡眠时间与自杀风险呈反向 J 形关联。与每晚睡眠 6-8 小时的人相比,睡眠时间为 0-4、4-6 和>8 小时的自杀风险调整后的危险比(95%置信区间)分别为 3.5(2.0-6.1)、1.5(1.1-1.9)和 1.5(1.1-2.0)。需要服用安眠药入睡的人(1.2%的参与者)自杀风险增加了 11 倍以上;入睡困难(11.5%的参与者)、频繁做梦(16.7%)和易醒(30.6%)分别与自杀风险增加 2.0 倍、1.6-1.3 倍相关。

结论

睡眠持续时间少于 6 小时、睡眠障碍和报告使用睡眠药物是自杀风险的标志物。在评估自杀风险时应评估睡眠问题。

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