Jackowska Marta, Poole Lydia
Department of Psychology, Whitelands College, University of Roehampton, United Kingdom.
Department of Epidemiology and Public Health, University College London, United Kingdom.
Sleep Med. 2017 Sep;37:60-65. doi: 10.1016/j.sleep.2017.02.004. Epub 2017 Mar 7.
This study investigated whether sleep problems, sleep duration and a combination of short or long sleep with sleep problems were predictive of depressive symptoms six years later.
Participants were 4545 men and women aged 50 years or older from the English Longitudinal Study of Ageing. Sleep problems were indexed through self-report enquiring about the most frequent insomnia symptoms including difficulties falling asleep, waking up several times a night and waking up in the morning feeling tired. Sleep duration was ascertained by asking about average sleep in the weeknight. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression scale.
Sleep problems were predictive of elevated depressive symptoms at follow-up (odds ratio [OR] = 1.36, 95% confidence interval [CI] = 1.19-1.56). When explored separately, waking up in the morning feeling tired (OR = 1.71, 95% CI = 1.24-2.37) followed by difficulties falling asleep (OR = 1.49, 95% CI = 1.06-2.11) were also predictors of future depressive symptoms. Compared to optimal duration, short (OR = 1.90, 95% CI = 1.34-2.71) but not long sleep hours were also linked to elevated depressive symptoms. Participants reporting short sleep hours combined with high sleep problems also had an elevated risk of depressive symptoms six years later (OR = 1.85, 95% CI = 1.15-3.00). Long sleep combined with high sleep problems was not predictive of depressive symptoms.
Short and disturbed sleep and their combination increase the risk of future depressive symptoms in older adults.
本研究调查了睡眠问题、睡眠时间以及短睡眠或长睡眠与睡眠问题的组合是否能预测六年后的抑郁症状。
研究对象为来自英国老龄化纵向研究的4545名50岁及以上的男性和女性。通过自我报告询问最常见的失眠症状来确定睡眠问题,这些症状包括入睡困难、夜间多次醒来以及早晨醒来感觉疲倦。通过询问工作日晚上的平均睡眠时间来确定睡眠时间。用流行病学研究中心抑郁量表测量抑郁症状。
睡眠问题可预测随访时抑郁症状的增加(比值比[OR]=1.36,95%置信区间[CI]=1.19-1.56)。单独研究时,早晨醒来感觉疲倦(OR=1.71,95%CI=1.24-2.37),其次是入睡困难(OR=1.49,95%CI=1.06-2.11)也是未来抑郁症状的预测因素。与最佳睡眠时间相比,短睡眠时间(OR=1.90,95%CI=1.34-2.71)而非长睡眠时间也与抑郁症状增加有关。报告短睡眠时间且睡眠问题较多的参与者在六年后出现抑郁症状的风险也较高(OR=1.85,95%CI=1.15-3.00)。长睡眠与高睡眠问题的组合不能预测抑郁症状。
睡眠不足和睡眠紊乱及其组合会增加老年人未来出现抑郁症状的风险。