Borch-Iohnsen B, Meltzer H M, Stenberg V, Reinskou T
Institute for Nutrition Research, University of Oslo, Norway.
Eur J Clin Nutr. 1990 Jan;44(1):23-8.
Serum ferritin was determined in 170 healthy Norwegian women (18-48 years; median age 36 years) including 23 blood donors. In women with serum ferritin less than or equal to 20 micrograms/l haemoglobin, serum iron and total iron binding capacity were determined. Women using oral contraceptives were excluded. Information was collected on use of contraceptive techniques, habits of iron prophylaxis, and duration of menses. About 40 per cent of the participants used the intra-uterine device. Geometric mean serum ferritin was 26.9 micrograms/l with a prevalence of 21.8 per cent with exhausted iron stores (serum ferritin less than 17 micrograms/l) among the non-donors. In the group with low to empty iron stores (serum ferritin less than or equal to 20 micrograms/l) 13 per cent had anaemia (Hb less than 120 g/l). This may correspond to 4.1 per cent among all the non-donors. The blood donors had a geometric mean serum ferritin of 20.4 micrograms/l and 30 per cent with empty stores. Our study shows that in the group of non-donors there was a tendency to higher prevalence of low or empty iron stores among IUD-users and premenopausal women. In addition to these groups the blood donors are at risk of iron deficiency.
对170名健康的挪威女性(年龄在18 - 48岁之间;中位年龄36岁)进行了血清铁蛋白检测,其中包括23名献血者。对于血清铁蛋白小于或等于20微克/升血红蛋白的女性,检测了血清铁和总铁结合力。使用口服避孕药的女性被排除在外。收集了有关避孕技术使用情况、铁预防习惯和月经持续时间的信息。约40%的参与者使用宫内节育器。非献血者的几何平均血清铁蛋白为26.9微克/升,铁储备耗尽(血清铁蛋白小于17微克/升)的患病率为21.8%。在铁储备低至耗尽(血清铁蛋白小于或等于20微克/升)的组中,13%的人患有贫血(血红蛋白小于120克/升)。这可能相当于所有非献血者中的4.1%。献血者的几何平均血清铁蛋白为20.4微克/升,30%的人储备耗尽。我们的研究表明,在非献血者组中,宫内节育器使用者和绝经前女性中铁储备低或耗尽的患病率有升高趋势。除了这些人群外,献血者也有缺铁风险。