Department of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, Fla. 32610, USA.
Neuroepidemiology. 2013;41(1):2-6. doi: 10.1159/000345138. Epub 2013 Mar 20.
Epidemiological studies have shown adverse short-term effects of air pollution on health including cardiovascular morbidity and mortality. However, air pollution-related stroke has received less attention.
In this study, we performed a time-stratified case-crossover analysis to evaluate the relationships between stroke hospital admissions and O3, among patients aged 65 years and older in Allegheny County, Pa., USA, between 1994 and 2000. We also examined whether the effects of air pollutants differed across strata defined by patient demographic characteristics and ambient temperature.
Exposures to O3 on the current day increase the risk of total stroke hospitalization by 1.9% (95% CI: 0.01-3.8) per interquartile range increase in concentration. Furthermore, the results suggest that males were more sensitive to adverse health effects of O3 on stroke hospitalization than females.
These results suggest that O3 has an adverse effect on stroke hospitalization. Specific patient subgroups, such as males, may be at increased risk.
流行病学研究表明，空气污染对健康存在短期不良影响，包括心血管病发病率和死亡率。然而，与空气污染相关的中风问题还没有得到足够的重视。
本研究在美国宾夕法尼亚州阿勒格尼县，于 1994 年至 2000 年间，针对年龄在 65 岁及以上的患者，采用时间分层病例交叉分析方法，评估了 O3 与中风住院之间的关系。我们还检验了污染物的影响是否因患者人口统计学特征和环境温度的不同而存在差异。
O3 浓度每增加一个四分位距，总体中风住院风险就会增加 1.9%（95%置信区间：0.01-3.8）。此外，结果提示男性对 O3 导致中风住院的不良健康影响比女性更敏感。
这些结果表明，O3 对中风住院有不利影响。某些特定的患者亚组，如男性，可能面临更高的风险。
