Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece.
Mar Drugs. 2013 Apr 2;11(4):1104-12. doi: 10.3390/md11041104.
Three new dolastane diterpenes (1-3) and five previously reported perhydroazulenes were isolated from the organic extracts of the brown alga Dilophus spiralis. The structure elucidation and the assignment of the relative configurations of the isolated natural products were based on extensive analyses of their spectroscopic data, whereas the absolute configuration of metabolite 2 was determined through its chemical conversion to a previously isolated compound of known configuration.
从棕色海藻 Dilophus spiralis 的有机提取物中分离得到三种新的达玛烷二萜（1-3）和五种先前报道的过氧薁。通过对其光谱数据的广泛分析，阐明了分离得到的天然产物的结构并确定了它们的相对构型，而代谢产物 2 的绝对构型则通过其化学转化为先前分离得到的具有已知构型的化合物来确定。
