Suzuki Minoru, Yamada Hiroko, Kurata Kazuya
Division of Material Science, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, Japan.
J Nat Prod. 2002 Feb;65(2):121-5. doi: 10.1021/np010234b.
In our continuing efforts to study the presence of biologically active compounds that control seaweed-herbivore interactions, we examined the presence of such chemicals in freshly collected Dilophus okamurae Dawson. Our results demonstrated the presence of two diterpenoids, named dictyterpenoid A (1) and dictyterpenoid B (2), having a novel carbon skeleton, along with 10 known diterpenes, 3-12. The structures of these novel metabolites were elucidated by spectroscopic and chemical methods. The isolated compounds showed feeding-deterrent activity against the young abalone Haliotis discus hannai.
在我们持续研究控制海藻与食草动物相互作用的生物活性化合物的过程中，我们检测了新鲜采集的冈村双眉藻（Dilophus okamurae Dawson）中此类化学物质的存在情况。我们的结果表明，存在两种具有新型碳骨架的二萜类化合物，分别命名为双网藻二萜A（1）和双网藻二萜B（2），以及10种已知的二萜类化合物（3 - 12）。通过光谱和化学方法阐明了这些新型代谢物的结构。分离出的化合物对幼龄皱纹盘鲍（Haliotis discus hannai）显示出拒食活性。
