PDE8A runs interference to limit PKA inhibition of Raf-1.
作者信息
Maurice Donald H
机构信息
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada K7L 3N6.
出版信息
Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6248-9. doi: 10.1073/pnas.1303920110. Epub 2013 Apr 2.
Abstract
摘要
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Phosphodiesterase-8A binds to and regulates Raf-1 kinase.磷酸二酯酶-8A 与 Raf-1 激酶结合并调节其活性。
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