Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA.
J Sex Med. 2013 Jul;10(7):1867-73. doi: 10.1111/jsm.12136. Epub 2013 Apr 3.
Available methods to evaluate men with Peyronie's disease (PD) are limited by the inability to accurately and reproducibly measure penile deformity. AIM.: The study aims to evaluate the performance of a smartphone application for the measurement of penile curvature and narrowing.
A smartphone application, the University of Washington Peyronie's Examination Network (UWPEN), was developed for this purpose. To assess penile curvature, 15 single cylinders of malleable penile prostheses were molded to varying curvature angles. Three blinded observers nonsequentially measured the angle of curvature for each prosthetic cylinder using a protractor, goniometer, and UWPEN. To assess girth narrowing, six clay models of the penile shaft were constructed to represent conditions of normal, partial hourglass, circumferential hourglass, and pencil narrowing. Girth was measured using a ruler and UWPEN by the same blinded observers.
Statistical analyses compared intertest, interobserver, and intraobserver reliability using the interclass correlation coefficient (ICC). An ICC above 0.75 indicates excellent reproducibility among measurements.
Intertest reliability for angle measurements yielded an ICC for the three methods of 1.000. Separately, the ICC for UWPEN vs. the goniometer and protractor was 0.999 and 0.999, respectively. The interobserver ICC for UWPEN, goniometer, and protractor was 0.998, 0.999, and 1.000, respectively. Intertest reliability for girth narrowing measurements yielded an ICC of 0.991. The interobserver ICC for girth narrowing for UWPEN and the ruler was 0.978 and 0.986, respectively. Intraobserver ICC for angle measurements and girth narrowing showed high reliability for all observers and methods.
The performance of UWPEN is comparable with and highly correlated with angle measurements obtained from the goniometer and protractor as well as with girth narrowing measurements obtained from a ruler. Measurements are reproducible among different observers. UWPEN may provide a noninvasive, accurate, reliable, and widely accessible method to characterize and track PD over time.
目前评估患有 Peyronie 病（PD）的男性的方法受到限制，因为无法准确和可重复地测量阴茎畸形。
本研究旨在评估一种用于测量阴茎弯曲和狭窄的智能手机应用程序的性能。
为此开发了一种名为华盛顿大学 Peyronie 检查网络（UWPEN）的智能手机应用程序。为了评估阴茎弯曲度，将 15 个可弯曲阴茎假体的单个圆柱体模制成不同的弯曲角度。三位盲法观察者依次使用量角器、测角器和 UWPEN 测量每个假体圆柱体的弯曲角度。为了评估周长变窄，构建了六个阴茎轴的粘土模型，以代表正常、部分沙漏形、周向沙漏形和铅笔形变窄的情况。同样的盲法观察者使用尺子和 UWPEN 测量周长。
使用组内相关系数（ICC）比较测试间、观察者间和观察者内的可靠性。ICC 大于 0.75 表示测量值之间具有极好的可重复性。
三种方法的角度测量的测试间可靠性的 ICC 为 1.000。单独使用 UWPEN 与测角器和量角器的 ICC 分别为 0.999 和 0.999。UWPEN、测角器和量角器的观察者间 ICC 分别为 0.998、0.999 和 1.000。周长变窄测量的测试间可靠性的 ICC 为 0.991。UWPEN 和尺子的观察者间周长变窄的 ICC 分别为 0.978 和 0.986。所有观察者和方法的角度测量和周长变窄的观察者内 ICC 均显示出高度可靠性。
UWPEN 的性能与测角器和量角器获得的角度测量以及与尺子获得的周长变窄测量相当且高度相关，并且在不同观察者之间具有可重复性。UWPEN 可能提供一种非侵入性、准确、可靠且广泛适用的方法，用于随时间评估和跟踪 PD。
