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FOXO4 is necessary for neural differentiation of human embryonic stem cells.
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Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines.
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FOXO4-SP6 axis controls surface epithelium commitment by mediating epigenomic remodeling.
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FoxO transcription factors actuate the formative pluripotency specific gene expression programme.
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1
FoxO6 regulates memory consolidation and synaptic function.
Genes Dev. 2012 Dec 15;26(24):2780-801. doi: 10.1101/gad.208926.112. Epub 2012 Dec 7.
2
Increased proteasome activity in human embryonic stem cells is regulated by PSMD11.
Nature. 2012 Sep 13;489(7415):304-8. doi: 10.1038/nature11468.
3
RPN-6 determines C. elegans longevity under proteotoxic stress conditions.
Nature. 2012 Sep 13;489(7415):263-8. doi: 10.1038/nature11315.
4
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.
Cell Stem Cell. 2009 Nov 6;5(5):540-53. doi: 10.1016/j.stem.2009.09.013.
5
FoxO3 regulates neural stem cell homeostasis.
Cell Stem Cell. 2009 Nov 6;5(5):527-39. doi: 10.1016/j.stem.2009.09.014.
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Biological and chemical approaches to diseases of proteostasis deficiency.
Annu Rev Biochem. 2009;78:959-91. doi: 10.1146/annurev.biochem.052308.114844.
7
FOXO3A genotype is strongly associated with human longevity.
Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13987-92. doi: 10.1073/pnas.0801030105. Epub 2008 Sep 2.
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The plasticity of aging: insights from long-lived mutants.
Cell. 2005 Feb 25;120(4):449-60. doi: 10.1016/j.cell.2005.02.002.
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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice.
Nature. 2003 Jan 9;421(6919):182-7. doi: 10.1038/nature01298. Epub 2002 Dec 4.

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