Department of Gastroenterology, Xi'an Central Hospital, College of Medicine, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Neurogastroenterol Motil. 2013 Jul;25(7):617-e467. doi: 10.1111/nmo.12124. Epub 2013 Apr 2.
Functional gastrointestinal disorders (FGIDs) are disorders with chronic and recurring gastrointestinal symptoms. This study investigated the prevalence of FGIDs, assessed the association between FGIDs and psychosocial factors, and identified potential risk factors for FGIDs in a population in Xi'an, China.
Of 752 recruited residents in Xi'an, 720 were selected for an epidemiological survey using a cluster sampling method. All subjects were interviewed face-to-face to complete the Chinese version of ROME III FGIDs questionnaire, the Symptom Check-List-90, the Eysenck Personality Questionnaire, a Life Event Scale, and a questionnaire regarding personal childhood adversity. The prevalence of FGIDs and associations between FGIDs and psychosocial factors were determined using EpiData Software. Logistic regression analysis was performed to identify the potential risk factors for FGIDs.
The prevalence of FGIDs in this sample population was 14.3% (103/720). There were 13 (1.8%) cases of overlap of different FGIDs. No significant difference in the prevalence of FGIDs was observed between men and women. Alcohol intake and smoking habits were significantly associated with the presence of FGIDs. The presence of FGIDs was significantly associated with psychological factors and influences such as personality type, life events, childhood adversity, and psychopathology. The potential risk factors for contracting FGIDs were certain life events, childhood adversity, somatization, and a hostile affect (P < 0.001).
CONCLUSIONS & INFERENCES: The prevalence of FGIDs and overlap syndrome in Xi'an, China was lower than that reported in other countries. There was a strong correlation between specific lifestyle habits and psychosocial characteristics and the presence of FGIDs.
功能性胃肠病（FGIDs）是一种慢性和反复发作的胃肠道疾病。本研究调查了 FGIDs 的流行情况，评估了 FGIDs 与心理社会因素之间的关系，并确定了中国西安人群中 FGIDs 的潜在危险因素。
在西安招募的 752 名居民中，采用聚类抽样方法选择了 720 名居民进行流行病学调查。所有受试者均进行面对面访谈，以完成中文版罗马 III FGIDs 问卷、症状自评量表-90、艾森克人格问卷、生活事件量表和个人童年逆境问卷。使用 EpiData 软件确定 FGIDs 的流行情况和 FGIDs 与心理社会因素之间的关系。采用 Logistic 回归分析确定 FGIDs 的潜在危险因素。
本样本人群 FGIDs 的患病率为 14.3%（103/720）。不同 FGIDs 重叠的病例为 13 例（1.8%）。男女 FGIDs 的患病率无显著差异。饮酒和吸烟习惯与 FGIDs 的存在显著相关。FGIDs 的存在与心理因素和人格类型、生活事件、童年逆境和精神病理学等影响显著相关。发生 FGIDs 的潜在危险因素是某些生活事件、童年逆境、躯体化和敌对情绪（P<0.001）。
中国西安 FGIDs 和重叠综合征的患病率低于其他国家报告的患病率。特定的生活习惯和心理社会特征与 FGIDs 的存在密切相关。
