Ito Toshiro, Kawaharada Nobuyoshi, Kurimoto Yoshihiko, Watanabe Atsushi, Tachibana Kazutoshi, Harada Ryo, Maeda Toshiyuki, Hashiguchi Hitoki, Hashimoto Makoto, Higami Tetsuya
Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University, School of Medicine, Hokkaido, Japan.
Ann Vasc Dis. 2010;3(2):111-6. doi: 10.3400/avd.AVDoa01007. Epub 2010 Sep 10.
The aim of this study is to investigate the positive association between the presence of renal cysts and AAA.
A retrospective chart review on the clinical data of 396 consecutive patients, who underwent CT scans for preoperative evaluation of thoracic and cardiovascular surgery in Sapporo Medical University from the period of January 2007 to December 2008, was conducted.
When comparing patients with renal cysts (n = 164) to those without (n = 233), there was a statistically significant difference between the presence of renal cysts and male gender (p = 0.007), hypertension (p = 0.003), and AAA (p < 0.001) on univariate analysis. In addition, when comparing patients with AAA to those without, although COPD but not AAA was associated with renal cysts in less than 65 years old, the presence of renal cysts was the strongest association with AAA among patients belonging to the 65 to 74 years old group and over 75 years old group on multivariate analysis.
There is a statistically higher incidence of renal cysts in patients with AAA compared to patients without AAA in the group of elder cardiovascular patients. It is likely that AAA and renal cysts share a common pathogenesis.
本研究旨在探讨肾囊肿与腹主动脉瘤（AAA）之间的正相关关系。
对2007年1月至2008年12月期间在札幌医科大学接受胸部和心血管手术术前CT扫描的396例连续患者的临床资料进行回顾性图表分析。
在单因素分析中，将有肾囊肿的患者（n = 164）与无肾囊肿的患者（n = 233）进行比较时，肾囊肿的存在与男性性别（p = 0.007）、高血压（p = 0.003）和腹主动脉瘤（p < 0.001）之间存在统计学显著差异。此外，将有腹主动脉瘤的患者与无腹主动脉瘤的患者进行比较时，虽然在65岁以下患者中慢性阻塞性肺疾病（COPD）而非腹主动脉瘤与肾囊肿相关，但在多因素分析中，在65至74岁组和75岁以上组患者中，肾囊肿的存在与腹主动脉瘤的相关性最强。
在老年心血管疾病患者组中，与无腹主动脉瘤的患者相比，有腹主动脉瘤的患者肾囊肿的发生率在统计学上更高。腹主动脉瘤和肾囊肿可能具有共同的发病机制。
