Department of Dermatology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Suite B260, Milwaukee, WI 53226, USA.
Dermatol Clin. 2013 Apr;31(2):289-301. doi: 10.1016/j.det.2012.12.006.
Infantile hemangioma is the most common soft tissue tumor of childhood. Despite its frequency, it has only been in the last decade that these lesions have been better characterized and become the subject of significant clinical and translational research. Although most infantile hemangiomas are uncomplicated and do not require intervention, they can be a significant source of parental distress, cosmetic disfigurement, and morbidity. The wide spectrum of disease in the morphology of these lesions and in their behavior has made it difficult to predict the need for treatment and has made it challenging to establish a standardized approach to management.
婴儿血管瘤是儿童中最常见的软组织肿瘤。尽管其发病率很高,但直到过去十年,人们才对这些病变有了更好的认识,并使其成为重要的临床和转化研究的主题。尽管大多数婴儿血管瘤并不复杂,不需要干预,但它们可能会给父母带来很大的困扰,导致孩子出现外貌畸形和发病。这些病变在形态和行为上的广泛表现,使得难以预测治疗的必要性,并使得建立标准化的管理方法具有挑战性。