Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi, India.
Indian J Dermatol Venereol Leprol. 2010 Sep-Oct;76(5):469-75. doi: 10.4103/0378-6323.69048.
Infantile hemangiomas (IH) are neoplastic proliferations of endothelial cells, characterized by a period of growth after birth, and eventual spontaneous involution. The course can be uneventful, culminating in spontaneous resolution; or it may be marked by complications such as bleeding; ulceration; infection; visual, feeding and breathing compromise; cosmetic and life-threatening complications such as congestive heart failure. Recognition of associated syndromes and impending complications of hemangiomas is of utmost importance. Great advances have taken place in the nomenclature, pathogenesis, immunohistochemistry, diagnostic workup and management of hemangiomas in the recent years. This article reviews current advances in the understanding of the pathogenesis, diagnostic tools, medical and surgical modalities of treatment for infantile hemangiomas.
婴儿血管瘤(IH)是内皮细胞的肿瘤性增生,其特征是出生后经历一段生长期,最终自发消退。其病程可能平稳,最终自发消退;也可能出现并发症,如出血、溃疡、感染、视觉、喂养和呼吸障碍、美容和危及生命的并发症,如充血性心力衰竭。认识到血管瘤相关综合征和即将发生的并发症非常重要。近年来,在血管瘤的命名、发病机制、免疫组织化学、诊断检查和治疗管理方面取得了重大进展。本文综述了目前对婴儿血管瘤发病机制、诊断工具、内科和外科治疗方法的理解进展。