Department of Obstetrics & Gynecology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA.
Fertil Steril. 2013 Jul;100(1):214-8. doi: 10.1016/j.fertnstert.2013.03.010. Epub 2013 Apr 1.
To determine whether manifestations of polycystic ovary syndrome (PCOS), particularly androgen excess, differ between Caucasian and Asian women in the San Francisco Bay Area.
Cross-sectional study.
Multidisciplinary PCOS clinic at a tertiary academic center.
PATIENT(S): 121 Caucasian and 28 Asian women, aged 18-44, examined between 2006 and 2011 with PCOS verified by a reproductive endocrinologist and dermatologist according to the Rotterdam criteria.
INTERVENTION(S): Transvaginal ultrasounds, comprehensive dermatologic exams, and serum testing.
MAIN OUTCOME MEASURE(S): Hirsutism defined as a modified Ferriman-Gallwey (mFG) score ≥ 8, acne, androgenic alopecia, and biochemical hyperandrogenism.
RESULT(S): Caucasian and Asian women had a similar prevalence of all measures of androgen excess. Both groups had similar total mFG scores and site-specific mFG scores, except Asian women had a lower site-specific mFG score for the chest. Although Asian women were more likely to use laser hair removal, the results were unchanged when the women with a history of laser hair removal were excluded.
CONCLUSION(S): Caucasian and Asian women with PCOS living in the same geographic region had a similar prevalence of hirsutism as well as other markers for androgen excess. Further studies are necessary to evaluate the need for ethnic-specific mFG scores in women with PCOS.
确定多囊卵巢综合征（PCOS）的表现，尤其是高雄激素血症，在旧金山湾区的白种人和亚洲女性中是否存在差异。
横断面研究。
三级学术中心的多学科 PCOS 诊所。
121 名白种人和 28 名亚洲女性，年龄 18-44 岁，于 2006 年至 2011 年期间经生殖内分泌学家和皮肤科医生根据 Rotterdam 标准确诊为 PCOS，并进行了阴道超声、全面皮肤科检查和血清检测。
无。
高雄激素血症的定义为改良 Ferriman-Gallwey（mFG）评分≥8、痤疮、雄激素性脱发和生化高雄激素血症。
白种人和亚洲女性的所有雄激素过多的测量指标患病率相似。两组的总 mFG 评分和特定部位的 mFG 评分相似，除了亚洲女性的胸部特定部位的 mFG 评分较低。尽管亚洲女性更倾向于使用激光脱毛，但在排除有激光脱毛史的女性后，结果仍未改变。
生活在同一地理区域的白种人和亚洲 PCOS 女性的多毛症以及其他雄激素过多的标志物患病率相似。需要进一步研究来评估 PCOS 女性是否需要特定种族的 mFG 评分。
