Zhang Chen, He Hong, Ngan Peter
Department of Orthodontics, School and Hospital of Stomatology, and Key Lab for Oral Biomedical Engineering, Ministry of Education, Wuhan University, Wuhan, Hubei, People's Republic of China.
Sleep Breath. 2013 Dec;17(4):1309-14. doi: 10.1007/s11325-013-0840-5. Epub 2013 Apr 6.
Oral appliances are increasingly advocated as a treatment option for obstructive sleep apnea (OSA). However, it is not clear how the different designs influence treatment efficacy in children. The aim of this study was to investigate the effects of twin block (TB) appliance on children with OSA and mandibular retrognathia.
A total of 46 children (31 males, 15 females, aged 9.7 ± 1.5 years, BMI: 18.1 ± 1.04 kg/m(2)) diagnosed with mandibular retrognathia and OSA by polysomnography (PSG) and with no obesity or adenotonsillar hypertrophy were recruited for the study. Patients in the treatment group were instructed to wear the twin block oral appliance full time for an average of 10.8 months. The efficacy of treatment was determined by monitoring the PSG and cephalometric changes before and after appliance removal. Data were analyzed using paired t test.
Results showed an improvement in patient's facial profile after treatment with the TB appliance. The average AHI index decreased from 14.08 ± 4.25 to 3.39 ± 1.86 (p < 0.01), and the lowest SaO2 increased from 77.78 ± 3.38 to 93.63 ± 2.66 (p < 0.01). Cephalometric measurements showed a significant increase in the superior posterior airway space, middle airway space, SNB angle and facial convexity which indicate an enhancement in mandibular growth, and reduction in the soft palate length.
This preliminary study suggests that twin block appliance may improve the patient's facial profile and OSA symptoms in a group of carefully selected children presented with both OSA and mandibular retrognathia symptoms.
口腔矫治器作为阻塞性睡眠呼吸暂停(OSA)的一种治疗选择越来越受到推崇。然而,不同设计如何影响儿童的治疗效果尚不清楚。本研究的目的是调查双阻板(TB)矫治器对患有OSA和下颌后缩的儿童的影响。
通过多导睡眠图(PSG)诊断为下颌后缩和OSA且无肥胖或腺样体扁桃体肥大的46名儿童(31名男性,15名女性,年龄9.7±1.5岁,BMI:18.1±1.04kg/m²)被纳入研究。治疗组患者被指示全天佩戴双阻板口腔矫治器,平均佩戴10.8个月。通过监测去除矫治器前后的PSG和头影测量变化来确定治疗效果。数据采用配对t检验进行分析。
结果显示,使用TB矫治器治疗后患者的面部轮廓得到改善。平均呼吸暂停低通气指数(AHI)从14.08±4.25降至3.39±1.86(p<0.01),最低血氧饱和度(SaO₂)从77.78±3.38升至93.63±2.66(p<0.01)。头影测量显示,上气道后间隙、中气道间隙、SNB角和面部凸度显著增加,这表明下颌生长增强,软腭长度缩短。
这项初步研究表明,双阻板矫治器可能改善一组同时患有OSA和下颌后缩症状的精心挑选儿童的面部轮廓和OSA症状。