Pollithy S, Celik N, Höh H, Dithmar S
Schwerpunkt Retinologie, Universitäts-Augenklinik Heidelberg, Heidelberg.
Ophthalmologe. 2013 May;110(5):460-3. doi: 10.1007/s00347-012-2741-6.
With respect to the increasing number of patients and the risk and burden for patients caused by injections, a reduction in the number and frequency of injections with vascular endothelial growth factor (VEGF) inhibitors in exudative age-related macular degeneration (ARMD) is desirable. Stereotactic low-voltage x-ray irradiation seems to be a promising approach. For this purpose the Oraya system is available and has shown positive results in initial studies. Pending presentation of phase II and III study data this adjuvant irradiation should only be used in clinical trials.
鉴于渗出性年龄相关性黄斑变性（ARMD）患者数量不断增加以及注射给患者带来的风险和负担，减少血管内皮生长因子（VEGF）抑制剂的注射次数和频率是可取的。立体定向低电压X射线照射似乎是一种有前景的方法。为此，Oraya系统可供使用，并且在初步研究中已显示出积极结果。在II期和III期研究数据公布之前，这种辅助照射仅应在临床试验中使用。
