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HGV-HCV/HBV co-infection in India: A pilot study.

作者信息

Pathare Amruta D, Deshpande Anand S

机构信息

Department of Research, Transfusion Medicine, P.D. Hinduja National Hospital and Medical Research Centre, Mumbai, India.

出版信息

Asian J Transfus Sci. 2013 Jan;7(1):48-50. doi: 10.4103/0973-6247.106734.

DOI:10.4103/0973-6247.106734
PMID:23559765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3613662/
Abstract

BACKGROUND

Hepatitis G virus (HGV) is newly identified virus, transmitted by infected blood and blood products. Effect of HGV infection on liver diseases is not well known.

AIMS

Co-infection of HGV with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection has been reported however; very limited data is available from India. Therefore, we have performed a pilot study for the presence of co-infection of HGV in chronic liver disease patients.

SETTING AND DESIGN

The study was performed in research laboratory at P.D. Hinduja National hospital and Medical research center, Mahim, Mumbai. Prospective study was designed.

METHODS AND MATERIALS

Forty HBV, HCV related chronic liver disease patients were studied. Forty randomly selected voluntary healthy blood donors visiting our blood bank were included as controls. Serum bilirubin, alanine aminotransferase (ALT), Aspartate aminotransferase (AST) and alkaline phosphatase (ALP) were estimated. HGV infection was detected by using reverse transcriptase molony murine leukemia virus (M-MLV) with the help of HGV 340/625IC kit (Sacace, Italy).

RESULTS AND CONCLUSION

One HCV positive patient had infection with HGV among 40 HBV/HCV chronic liver disease patients.

摘要

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Hepatitis G Virus: Prevalence in Blood Donors in Armed Forces.庚型肝炎病毒:武装部队献血者中的流行情况。
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