Williams J M, Healy D, Teasdale J D, White W, Paykel E S
MRC Applied Psychology Unit, University of Cambridge, Addenbrooke's Hospital.
Psychol Med. 1990 May;20(2):375-81. doi: 10.1017/s0033291700017694.
Forty-four patients who met criteria for major depressive disorder were assessed for presence of dysfunctional attitudes and negative self-schema on admission. After six weeks, of sixteen patients who had shown high dysfunctional attitudes, six (35%) had not recovered. By contrast, of seventeen patients who had been equally severely depressed at the outset, but had low dysfunctional attitudes, only one (6%) had not recovered. The rating by the patients of themselves, as opposed to their attitudes, did not however predict. Thirty-one patients were tested six months later. Twenty-one (68%) remained asymptomatic, ten patients had relapsed or not responded to treatment, but neither type of admission measure predicted the state at this point. This is consistent with previous evidence which suggests that vulnerable attitudes assessed when symptomatic predict recovery, but that for prediction of relapse, cognitive measures need to be used when the patient is asymptomatic.
对44名符合重度抑郁症标准的患者入院时评估其功能失调性态度和消极自我图式的存在情况。六周后，在16名表现出高度功能失调性态度的患者中，有6名（35%）未康复。相比之下，在17名一开始同样严重抑郁但功能失调性态度较低的患者中，只有1名（6%）未康复。然而，患者对自身的评分（与他们的态度不同）并不能预测结果。31名患者在六个月后接受测试。21名（68%）仍无症状，10名患者复发或对治疗无反应，但两种入院测量方法均无法预测此时的状态。这与之前的证据一致，即有症状时评估的易损态度可预测康复，但对于复发的预测，需要在患者无症状时使用认知测量方法。
