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在体和体内实验模型作为研究抗肿瘤药物对膀胱癌疗效的工具。

In vitro and in vivo experimental models as tools to investigate the efficacy of antineoplastic drugs on urinary bladder cancer.

机构信息

Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria.

出版信息

Anticancer Res. 2013 Apr;33(4):1273-96.

PMID:23564765
Abstract

Several drugs have shown in vitro and in vivo pharmacological activity against urinary bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in vivo models of urinary bladder cancer and to review the advantages and limitations of both types of models, as well as the different methodologies applied for evaluating antineoplastic drug activity.

摘要

几种药物已显示出对膀胱癌的体外和体内药理学活性。本综述旨在汇编在膀胱癌的体外和体内模型中评估的不同药物，并回顾这两种模型的优缺点，以及评估抗肿瘤药物活性所应用的不同方法学。

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