Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, NBG, Building 10, Noerrebrogade 44, Aarhus C, 8000, Denmark,
Eur Arch Otorhinolaryngol. 2013 Nov;270(12):3163-7. doi: 10.1007/s00405-013-2474-4. Epub 2013 Apr 9.
Peritonsillar abscess (PTA) is a frequent complication to acute tonsillitis, in particular in adolescents and young adults. Smoking is most commonly initiated during adolescence and young adulthood. The study examines whether smoking increases the risk of PTA and whether smoking is associated with the bacterial findings in PTA. All patients with PTA admitted to the Ear-Nose-Throat Department at Aarhus University Hospital from January 2001 through December 2006 were included in the study. Age- and gender-stratified data on smoking habits in the Danish population and demographic data for Aarhus County for the same 6 years were obtained. Smoking status was available for 679 (80 %) of 847 patients with PTA. 247 (36 %) patients admitted to daily tobacco smoking. Age-stratified odds ratios of smokers compared to non-smokers, for developing PTA, were in the range of 1.9-4.7. Fusobacterium necrophorum and beta-hemolytic streptococci were equally distributed between smokers and non-smokers. Twenty nine percent of the higher incidence of PTA among males compared to females could be explained by a higher prevalence of smoking in males. After correcting for differences in smoking prevalence by gender, the risk of PTA was calculated to be 9.5 % higher among males than females. Smoking was associated with significantly increased risk of PTA in both males and females of all ages. No differences in the microbiological flora of smokers and non-smokers with PTA were found.
扁桃体周脓肿(PTA)是急性扁桃体炎的常见并发症,尤其是在青少年和年轻成年人中。吸烟通常在青少年和年轻成年人中开始。本研究旨在探讨吸烟是否会增加 PTA 的风险,以及吸烟是否与 PTA 中的细菌发现有关。
所有于 2001 年 1 月至 2006 年 12 月期间在奥胡斯大学医院耳鼻喉科住院的 PTA 患者均纳入本研究。获取了同期丹麦人口吸烟习惯的年龄和性别分层数据,以及奥胡斯郡的人口统计学数据。对 847 名 PTA 患者中的 679 名(80%)进行了吸烟状况分层数据。247 名(36%)患者承认每日吸烟。与不吸烟者相比,吸烟者发生 PTA 的年龄分层比值比在 1.9 至 4.7 之间。类杆菌属和β溶血性链球菌在吸烟者和不吸烟者之间分布均等。男性 PTA 发病率比女性高 29%,这可以归因于男性吸烟率较高。在按性别调整吸烟率差异后,男性 PTA 的风险比女性高 9.5%。无论年龄大小,吸烟与 PTA 的风险显著增加相关。在患有 PTA 的吸烟者和不吸烟者中,未发现微生物菌群存在差异。