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急性A型主动脉夹层的药物治疗联合急性肢体缺血的早期开放修复术可能避免主动脉手术。

Medical management of acute type a aortic dissection in association with early open repair of acute limb ischemia may prevent aortic surgery.

作者信息

Gionis Michalis N, Kaimasidis George, Tavlas Emmanouel, Kontopodis Nikolaos, Plataki Marina, Kafetzakis Alexandros, Ioannou Christos V

机构信息

Vascular Surgery Department, University of Crete Medical School, Heraklion, Greece ; Department of Thoracic Surgery, Regional General Hospital of Chania, Greece.

出版信息

Am J Case Rep. 2013;14:52-7. doi: 10.12659/AJCR.883793. Epub 2013 Feb 22.

Abstract

BACKGROUND

Acute type A aortic dissection (AAAD) is a cardiovascular emergency with a high potential for death. Rapid surgical treatment is indicated to prevent fatal complications. Aggressive appropriate medical management starts at first suspicion and is essential to prevent exacerbation or rupture of the dissection. Despite improved surgical techniques, perioperative care and the development of specialized cardiovascular centers, mortality remains high. Organ ischemia is a catastrophic manifestation of aortic dissection, demanding acute surgical intervention in specialized cardiovascular centers.

CASE REPORT

We present the case of a 62-year-old man with isolated acute limb ischemia due to an acute type A aortic dissection treated in a regional general hospital, without a specialized cardiovascular service, with immediate open malperfusion repair and aggressive medical management. The patient did not undergo further surgical aortic repair, and after a 30-month follow-up he remains symptom free and in good clinical condition, suggesting that although aortic surgery remains the gold standard for treatment of acute Type A dissection, appropriate medical management and early malperfusion repair may offer an initial limb- or life-saving procedure.

CONCLUSIONS

This staged approach gives clinicians more time to properly evaluate and transfer the patient to a specialized cardiovascular center, and in some cases may even offer a definite treatment.

摘要

背景

急性A型主动脉夹层(AAAD)是一种具有高死亡风险的心血管急症。需要迅速进行手术治疗以预防致命并发症。一旦怀疑应立即开始积极恰当的药物治疗,这对于防止夹层恶化或破裂至关重要。尽管手术技术、围手术期护理有所改进,且专业心血管中心不断发展,但死亡率仍然很高。器官缺血是主动脉夹层的灾难性表现,需要在专业心血管中心进行紧急手术干预。

病例报告

我们报告一例62岁男性患者,因急性A型主动脉夹层导致孤立性急性肢体缺血,在一家地区综合医院接受治疗,该医院没有专业心血管服务,对其进行了立即开放的灌注不良修复及积极的药物治疗。患者未接受进一步的主动脉手术修复,经过30个月的随访,他仍无症状且临床状况良好,这表明尽管主动脉手术仍然是治疗急性A型夹层的金标准,但恰当的药物治疗和早期灌注不良修复可能提供一种初步的挽救肢体或生命的方法。

结论

这种分阶段方法为临床医生提供了更多时间来正确评估患者并将其转至专业心血管中心,在某些情况下甚至可能提供确定性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ab/3614383/f3f611b96d96/amjcaserep-14-52-g001.jpg

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