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何时以及如何为A型主动脉夹层置换主动脉弓。

When and how to replace the aortic arch for type A dissection.

作者信息

Di Bartolomeo Roberto, Leone Alessandro, Di Marco Luca, Pacini Davide

机构信息

Cardiac Surgery Department, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

出版信息

Ann Cardiothorac Surg. 2016 Jul;5(4):383-8. doi: 10.21037/acs.2016.07.07.

Abstract

Acute type A aortic dissection (AAAD) remains one of the most challenging diseases in cardiothoracic surgery and despite numerous innovations in medical and surgical management, early mortality remains high. The standard treatment of AAAD requires emergency surgery of the proximal aorta, preventing rupture and consequent cardiac tamponade. Resection of the primary intimal tear and repair of the aortic root and aortic valve are well-established surgical principles. However, the dissection in the aortic arch and descending untreated aorta remains. This injury is associated with the risk of subsequent false lumen dilatation potentially progressing to rupture, true lumen compression and distal malperfusion. Additionally, the dilatation of the aortic arch, the presence of a tear and retrograde dissection can all be considered indication for a total arch replacement in AAAD. In such cases a more aggressive strategy may be used, from the classic aortic arch operation to a single stage frozen elephant trunk (FET) technique or a two-stage approach such as the classical elephant trunk (ET) or the recent Lupiae technique. Although these are all feasible solutions, they are also complex and time demanding techniques requiring experience and expertise, with an in the length of cardiopulmonary bypass and both myocardial and visceral ischemia. Effective methods of cerebral, myocardial as well visceral protection are necessary to obtain acceptable results in terms of hospital mortality and morbidity. Moreover, a correct assessment of the anatomy of the dissection, through the preoperative angio CT scan, in addition to the clinical condition of the patients, remain the decision points for the best arch repair strategy to use in AAAD.

摘要

急性A型主动脉夹层(AAAD)仍然是心胸外科中最具挑战性的疾病之一,尽管在医疗和手术管理方面有诸多创新,但早期死亡率仍然很高。AAAD的标准治疗需要对升主动脉进行急诊手术,以防止破裂及随之而来的心脏压塞。切除原发内膜破口以及修复主动脉根部和主动脉瓣是既定的手术原则。然而,主动脉弓和未处理的降主动脉夹层仍然存在。这种损伤与随后假腔扩张进而可能发展为破裂、真腔受压和远端灌注不良的风险相关。此外,主动脉弓扩张、存在破口以及逆行夹层都可被视为AAAD全弓置换的指征。在这种情况下,可能会采用更积极的策略,从经典的主动脉弓手术到单阶段的“冰冻象鼻”(FET)技术或两阶段方法,如经典的“象鼻”(ET)或最近的卢皮亚技术。尽管这些都是可行的解决方案,但它们也是复杂且耗时的技术,需要经验和专业知识,并且体外循环时间长,心肌和内脏都会出现缺血。为了在医院死亡率和发病率方面获得可接受的结果,有效的脑、心肌以及内脏保护方法是必要的。此外,除了患者的临床状况外,通过术前血管CT扫描对夹层解剖结构进行正确评估,仍然是决定AAAD最佳弓部修复策略的关键因素。

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