马缨丹的体内毒性研究。
In vivo toxicity study of Lantana camara.
作者信息
Pour Badakhshan Mahdi, Sasidharan Sreenivasan
机构信息
Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Jalan Bedong-Semeling, Batu 3 1/2, Bukit Air Nasi, Bedong 08100, Kedah, Malaysia.
出版信息
Asian Pac J Trop Biomed. 2011 Jun;1(3):230-2. doi: 10.1016/S2221-1691(11)60033-6.
Abstract
OBJECTIVE
To investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina.
METHODS
The methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay.
RESULTS
All the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most toxic part of L. camara and may have potential as anticancer agent.
CONCLUSIONS
Methanolic extract of L. camara is relatively safe on short-term exposure.
摘要
目的
研究马缨丹（Lantana camara）各部位（根、茎、叶、花和果实）的甲醇提取物对卤虫（Artemia salina）的毒性。
方法
对马缨丹的甲醇提取物进行卤虫活体致死率测定试验。
结果
所有受试提取物对卤虫幼虫的毒性都很低。结果表明，根提取物是马缨丹毒性最大的部位，可能具有抗癌潜力。
结论
短期接触马缨丹甲醇提取物相对安全。
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