Resolution pattern of jaundice among children presenting with severe malaria in rural South-West Nigeria.
作者信息
Osonuga O A, Osonuga A, Osonuga A A, Osonuga I O
机构信息
Department of Pharmacology and Physiology, University of Cape Coast, Cape Coast, Ghana ; School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.
出版信息
Asian Pac J Trop Biomed. 2012 Jul;2(7):551-3. doi: 10.1016/S2221-1691(12)60095-1.
OBJECTIVE
To compare the pattern of jaundice resolution among children with severe malaria treated with quinine and artemether.
METHODS
Thirty two children who fulfilled the inclusion criteria were recruited for the study from two hospitals with intensive care facilities. They were divided into two groups; 'Q' and 'A', receiving quinine and artemether, respectively. Jaundice was assessed by clinical examination.
RESULTS
Sixteen out of 32 children recruited (representing 50%) presented with jaundice on the day of recruitment. The mean age was (7.00°C2.56) years. On day 3, four patients in 'A' and six patients in 'Q' had jaundice. By day 7, no child had jaundice.
CONCLUSION
The study has shown that both drugs resolve jaundice although artemether relatively resolves it faster by the third day.
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