Department of Electrical and Computer Engineering, Democritus University of Thrace, 67100 Xanthi, Greece.
Comput Math Methods Med. 2013;2013:240182. doi: 10.1155/2013/240182. Epub 2013 Mar 14.
In this study a new method for asthma outcome prediction, which is based on Principal Component Analysis and Least Square Support Vector Machine Classifier, is presented. Most of the asthma cases appear during the first years of life. Thus, the early identification of young children being at high risk of developing persistent symptoms of the disease throughout childhood is an important public health priority.
The proposed intelligent system consists of three stages. At the first stage, Principal Component Analysis is used for feature extraction and dimension reduction. At the second stage, the pattern classification is achieved by using Least Square Support Vector Machine Classifier. Finally, at the third stage the performance evaluation of the system is estimated by using classification accuracy and 10-fold cross-validation.
The proposed prediction system can be used in asthma outcome prediction with 95.54 % success as shown in the experimental results.
This study indicates that the proposed system is a potentially useful decision support tool for predicting asthma outcome and that some risk factors enhance its predictive ability.
本研究提出了一种基于主成分分析和最小二乘支持向量机分类器的哮喘预后新方法。大多数哮喘病例出现在生命的最初几年。因此,早期识别儿童在整个儿童期持续出现疾病症状的高风险,是一个重要的公共卫生重点。
所提出的智能系统由三个阶段组成。在第一阶段,使用主成分分析进行特征提取和降维。在第二阶段,使用最小二乘支持向量机分类器进行模式分类。最后,在第三阶段,使用分类准确性和 10 折交叉验证来评估系统的性能。
实验结果表明,所提出的预测系统可用于哮喘预后预测,成功率为 95.54%。
本研究表明,该系统是一种有潜力的决策支持工具,可用于预测哮喘结局,并且某些风险因素增强了其预测能力。