Adachi T, Biesold D, Inanami O, Sato A
Department of Physiology, Tokyo Metropolitan Institute of Gerontology, Japan.
Brain Res. 1990 Apr 23;514(1):163-6. doi: 10.1016/0006-8993(90)90452-h.
The effect of a focal stimulation of the magnocellular nucleus of the basal forebrain at two different areas, the nucleus basalis of Meynert (NBM) and the substantia innominata (SI), on local cerebral blood flow (CBF) in the frontal, parietal and occipital cortices was examined in urethane-anesthetized rats. The stimulation, either electrically or chemically, of both the NBM and SI produced significant CBF increase in all these 3 cortices ipsilateral to the stimulation site. This fact suggests that activation of neurons originating in the NBM and SI produces widespread increases in local CBF in the ipsilateral cerebral cortex.
在氨基甲酸乙酯麻醉的大鼠中，研究了在基底前脑大细胞核对两个不同区域，即迈内特基底核（NBM）和无名质（SI）进行局部刺激，对额叶、顶叶和枕叶皮质局部脑血流量（CBF）的影响。对NBM和SI进行电刺激或化学刺激，均在刺激部位同侧的所有这三个皮质中引起显著的CBF增加。这一事实表明，源自NBM和SI的神经元激活会使同侧大脑皮质的局部CBF广泛增加。
