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巴西女性骨质疏松症相关因素:基于人群的家庭调查。

Factors associated with osteoporosis in Brazilian women: a population-based household survey.

机构信息

Department of Gynecology, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.

出版信息

Arch Osteoporos. 2013;8:138. doi: 10.1007/s11657-013-0138-z. Epub 2013 Apr 11.

Abstract

UNLABELLED

The aging of Brazilian population has been well-documented. A longer time since menopause, poor self-perception of health, and having arthrosis and balance problems are factors associated with postmenopausal osteoporosis. Poor self-perception of health, menopausal treatment with natural remedies, smoking, and decreased functional capacity are associated with early onset of the disease.

PURPOSE

This study aims to evaluate the prevalence of osteoporosis and its associated factors in Brazilian women over 50 years of age and to obtain information on factors related to the early onset of the disease.

METHODS

A cross-sectional study with 622 women over 50 years of age residing in Campinas/Brazil was conducted between May 10 and October 31, 2011 in the form of a population survey. A questionnaire was applied by trained interviewers. Osteoporosis was classified either as self-reported or as osteoporosis diagnosed by bone densitometry. Statistical analysis was carried out by chi-square test, Poisson regression analysis, and Cox multiple regression model.

RESULTS

The mean age of the women was 64.1 years. The prevalence of self-reported osteoporosis was 21.3 %. A longer time since menopause (prevalence ratios (PR), 1.04; 95 % CI, 1.03-1.05; p < 0.001); self-perception of health as fair/poor/very poor (PR, 1.73; 95 % CI, 1.29-2.33; p < 0.001); having arthrosis (PR, 1.83; 95 % CI, 1.30-2.59; p < 0.002) and having problems maintaining balance when taking a bath or going down stairs (PR, 1.52; 95 % CI, 1.07-2.14; p = 0.020) were associated with osteoporosis. The variables associated with early onset of the disease were: self-perception of health as fair/poor/very poor (coefficient, 0.77; p < 0.001), menopausal treatment with natural remedies (coefficient, 1.01; p < 0.001), smoking or having smoked >20 cigarettes/day (coefficient, 1.02; p = 0.003), and problems in running/lifting something heavy/practicing sports/doing heavy work (coefficient, 0.60; p = 0.029).

CONCLUSIONS

The results of this study have improved understanding of the factors associated with osteoporosis in the Brazilian population and may help identify those women who should undergo bone densitometry.

摘要

目的

本研究旨在评估巴西 50 岁以上女性骨质疏松症的患病率及其相关因素,并获取与疾病早期发病相关的因素信息。

方法

2011 年 5 月 10 日至 10 月 31 日,采用横断面研究方法,对巴西坎皮纳斯市 622 名 50 岁以上女性进行了一项以人群为基础的调查。由经过培训的调查员进行问卷调查。通过自我报告或骨密度仪诊断来确定骨质疏松症。采用卡方检验、泊松回归分析和 Cox 多回归模型进行统计学分析。

结果

女性的平均年龄为 64.1 岁。自我报告骨质疏松症的患病率为 21.3%。绝经时间较长(患病率比 1.04;95%可信区间 1.03-1.05;p<0.001);自我健康感知为一般/差/非常差(患病率比 1.73;95%可信区间 1.29-2.33;p<0.001);患有骨关节炎(患病率比 1.83;95%可信区间 1.30-2.59;p<0.002)和在洗澡或下楼梯时平衡有问题(患病率比 1.52;95%可信区间 1.07-2.14;p=0.020)与骨质疏松症相关。与疾病早期发病相关的变量包括:自我健康感知一般/差/非常差(系数 0.77;p<0.001)、绝经后采用天然疗法治疗(系数 1.01;p<0.001)、吸烟或每天吸烟>20 支(系数 1.02;p=0.003),以及在跑步/搬运重物/进行运动/从事重体力劳动方面存在问题(系数 0.60;p=0.029)。

结论

本研究结果提高了对巴西人群中与骨质疏松症相关因素的认识,有助于确定应进行骨密度检查的女性。

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