Lui Filho Jeffrey Frederico, Baccaro Luiz Francisco Cintra, Fernandes Tatiane, Conde Délio Marques, Costa-Paiva Lúcia, Pinto Neto Aarão Mendes
Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Departamento de Tocoginecologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Rev Bras Ginecol Obstet. 2015 Apr;37(4):152-8. doi: 10.1590/SO100-720320150005282.
To determine the average age at the onset of menopause and to investigate menopausal symptoms in women in a metropolitan region in Southeastern Brazil.
A descriptive, exploratory, cross-sectional study was conducted with 749 women (a population-based household survey). The dependent variable was the intensity of menopausal symptoms assessed by th Menopause Rating Scale (MRS). The independent variables were sociodemographic data, health-related habits and problems, self-perception of health, and gynecological background. Statistical analysis was carried out by the χ2 test and Poisson regression using the backward selection criteria.
The mean age of the women was 52.5 (± 4.4) years. With regard to menopausal status, 16% were premenopausal, 16% perimenopausal and 68% postmenopausal. The mean age at the onset of menopause was 46.5 (± 5.8) years. The intensity of menopausal symptoms was defined according to the median MRS score and was considered severe for values above 8. Depression/anxiety (PR = 1.8; 95%CI 1.5-2.2; p < 0.01), rheumatic diseases (PR 1.5; 95%CI 1.2-1.7; p < 0.01), self-perception of health as fair/poor/very poor (PR 1.4; 95% CI 1.2-1.7; p < 0.01), history of abortion (PR 1.3; 95%CI 1.1-1.4; p < 0.01), current or previous treatment for menopausal symptoms (PR 1.2; 95%CI 1.1-1.4; p < 0.01), peri- or postmenopausal status (PR 1.4; 95%CI 1.1-1.7; p < 0.01), number of normal deliveries > 1 (PR 1.2; 95%CI 1.02-1.4; p < 0.01) and asthma (PR 1.2; 95%CI 1.01-1.4; p < 0.01) were associated with more severe menopausal symptoms. Older age (PR 0.96; 95%CI 0.96-0.97; p < 0.01) was associated with less severe symptoms.
The severity of menopausal symptoms was related to a wild range of factors, especially presence of chronic diseases, a larger number of pregnancies, use of hormone therapy, and worse self-rated health. A better understanding of these factors can help to reduce the impact of symptoms on quality of life, and to identify groups of women who are likely to need more care during and beyond menopause.
确定巴西东南部一个大都市地区女性绝经开始的平均年龄，并调查其绝经症状。
对749名女性进行了一项描述性、探索性横断面研究（基于人群的家庭调查）。因变量是通过绝经评定量表（MRS）评估的绝经症状强度。自变量是社会人口统计学数据、与健康相关的习惯和问题、对健康的自我认知以及妇科背景。采用卡方检验和泊松回归，依据向后选择标准进行统计分析。
女性的平均年龄为52.5（±4.4）岁。关于绝经状态，16%为绝经前，16%为围绝经期，68%为绝经后。绝经开始的平均年龄为46.5（±5.8）岁。绝经症状强度根据MRS评分中位数确定，评分高于8分则被认为症状严重。抑郁/焦虑（PR = 1.8；95%CI 1.5 - 2.2；p < 0.01）、风湿性疾病（PR 1.5；95%CI 1.2 - 1.7；p < 0.01）、自我感觉健康状况为一般/较差/非常差（PR 1.4；95%CI 1.2 - 1.7；p < 0.01）、流产史（PR 1.3；95%CI 1.1 - 1.4；p < 0.01）、目前或既往接受过绝经症状治疗（PR 1.2；95%CI 1.
